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Results 1 - 10 of 21 > >>
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) - Bacillus subtilis sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) - Escherichia coli sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) - Escherichia coli sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ir
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) - Thermotoga maritima sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) - Bacillus subtilis PS832 sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) - Thermotoga maritima ATCC 43589 sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) Cys456 bears a persulfide group upon incubation with sulfurtransferase IscS and cysteine, no intermediate sulfur carrier protein is chemically required Escherichia coli sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) sulfane sulfur generated by IscS is transferred sequentially to ThiI and then to tRNA during the in vitro synthesis of 4-thiouridine Escherichia coli sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfide + adenylated-tRNA-uridine(position8) sulfide is able to replace IscS/cysteine as a substrate for 4-thiouridine synthesis Escherichia coli tRNA-4-thiouridine(position8) + ? - ?
Display the reaction diagram Show all sequences 2.8.1.B3sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) the biosynthesis of 4-thiouridine in Escherichia coli tRNA requires the action of both the thiamin pathway enzyme ThiI and the cysteine desulfurase IscS. IscS catalyzes sulfur transfer from L-cysteine to ThiI, which utilizes MgATP2- to activate uridine 8 in tRNA and transfers sulfur to give s4U. Outside of the modified uridine 8, there is no primary sequence requirement for substrate recognition. However, the secondary and tertiary structure restrictions appear sufficient to explain why s4U modification is limited in the cell to tRNA Escherichia coli sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP - ?
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