EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.B72 | Ac-WAEW-NH2 peptide + GDP-mannose |
- |
Caenorhabditis elegans |
? |
- |
? |
2.4.1.B72 | Ac-WAEWGEC-NH2 peptide + GDP-mannose |
- |
Caenorhabditis elegans |
? |
- |
? |
2.4.1.B72 | dolichyl D-mannosyl phosphate + MIG-21 protein |
C-mannosylation at a tryptophan residue |
Caenorhabditis elegans |
dolichyl phosphate + C-mannosylated MIG-21 protein |
- |
? |
2.4.1.B72 | dolichyl D-mannosyl phosphate + UNC-5 protein |
C-mannosylation at a tryptophan residue |
Caenorhabditis elegans |
dolichyl phosphate + C-mannosylated UNC-5 protein |
- |
? |
2.4.1.B72 | dolichyl D-mannosyl phosphate + WAKW |
in vitro assay using radiolabeled donor substrate and a synthetic acceptor peptide WAKW, which forms the minimal acceptor substrate |
Caenorhabditis elegans |
dolichyl phosphate + ? |
- |
? |
2.4.1.B72 | more |
cell surface receptors MIG-21 and UNC-5 are acceptor substrates of enzyme DPY-19 |
Caenorhabditis elegans |
? |
- |
? |
2.4.1.B72 | more |
C-mannosylation of tryptophan residues is an endoplasmic reticulum localized, DPY-19 enzyme-catalyzed reaction using the lipid-linked glycoside dolichol-phosphate-mannose as the donor substrate |
Caenorhabditis elegans |
? |
- |
? |
2.4.1.B72 | more |
C-mannosylation is initially described as a modification of the first tryptophan in the WxxW consensus sequence, but is also observed on tryptophans that are not part of this motif. In addition to WxxW, WxxC is also considered to be a consensus sequence for C-mannosylation |
Caenorhabditis elegans |
? |
- |
- |
2.4.1.B72 | more |
the enzyme can transfer mannose to adhesive thrombospondin type 1 repeats (TSRs) and type I cytokine receptors. Enzyme Dpy19 of Caenorhabditis elegans can transfer mannose to a short WXXW peptide |
Caenorhabditis elegans |
? |
- |
- |
2.4.1.B72 | more |
the single Caenorhabditis elegans C-mannosyltransferase DPY-19 mannosylates the first two tryptophans of a WxxWxxW motif |
Caenorhabditis elegans |
? |
- |
- |