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Results 1 - 6 of 6
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.4.1.26more hydroxymethylated DNA binding activities of wild-type and mutant enzymes, the enzyme undergoes a conformational change from a substrate-free open form to a closed substrate-binding form stabilized by several salt bridges and probably involving Ser106 and Glu22 Tequatrovirus T4 ? - ?
Display the reaction diagram Show all sequences 2.4.1.26UDP-glucose + hydroxymethylated DNA Glu22 seems not to be responsible for activation of the nucleophilic attack, Ser106 and Glu311 probably form a salt bridge in the closed enzyme formation, Glu311 is probably involved in interaction with UDP-glucose, Arg236, Arg256 and Met231 are probably involved in interaction with the DNA Tequatrovirus T4 UDP + glycosylated hydroxymethylated DNA - ?
Display the reaction diagram Show all sequences 2.4.1.26UDPglucose + 5-hydroxymethylcytosine containing DNA - Tequatrovirus T4 UDP + alpha-glucosyl-5-hydroxymethylcytosine containing DNA - ?
Display the reaction diagram Show all sequences 2.4.1.26UDPglucose + 5-hydroxymethylcytosine containing DNA - Escherichia phage T2 UDP + alpha-glucosyl-5-hydroxymethylcytosine containing DNA - ?
Display the reaction diagram Show all sequences 2.4.1.26UDPglucose + 5-hydroxymethylcytosine containing DNA extent of glucosylation varies between 50% and 80% of the amount of hydroxymethylcytosine residues calculated to be present, T4 DNA with no unsubstituted hydroxymethylcytosine groups does not serve as acceptor, T2 DNA: no activity with enzyme from T2-infected cells, small activity with enzyme from T4- and T6-infected cells Tequatrovirus T4 UDP + alpha-glucosyl-5-hydroxymethylcytosine containing DNA - ?
Display the reaction diagram Show all sequences 2.4.1.26UDPglucose + 5-hydroxymethylcytosine containing DNA extent of glucosylation varies between 50% and 80% of the amount of hydroxymethylcytosine residues calculated to be present, T4 DNA with no unsubstituted hydroxymethylcytosine groups does not serve as acceptor, T2 DNA: no activity with enzyme from T2-infected cells, small activity with enzyme from T4- and T6-infected cells Enterobacteria phage T6 UDP + alpha-glucosyl-5-hydroxymethylcytosine containing DNA - ?
Results 1 - 6 of 6
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