EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.372 | adenosyl-L-methionine + [histone H4]-N6,N6-dimethyl-L-lysine20 |
- |
Schizosaccharomyces pombe |
adenosyl-L-homocysteine + [histone H4]-N6,N6,N6-trimethyl-L-lysine20 |
- |
? |
2.1.1.372 | adenosyl-L-methionine + [histone H4]-N6,N6-dimethyl-L-lysine20 |
- |
Schizosaccharomyces pombe 972 |
adenosyl-L-homocysteine + [histone H4]-N6,N6,N6-trimethyl-L-lysine20 |
- |
? |
2.1.1.372 | more |
enzyme shows versatility in substrate recognition. In a pan-methylation assay of histone H3, H3K4me3 and H3K27me3 species are preferably detected rather than me1 and me2 species, and H3K79-me1 and -me2 species are favored against me3 species. NSD3 shows significant di-/tri-methylation of histone H4K20 |
Homo sapiens |
? |
- |
- |
2.1.1.372 | S-adenosyl-L-methionine + [histone H4]-L-lysine20 |
- |
Schizosaccharomyces pombe |
S-adenosyl-L-homocysteine + [histone H4]-N6-methyl-L-lysine20 |
- |
? |
2.1.1.372 | S-adenosyl-L-methionine + [histone H4]-L-lysine20 |
- |
Schizosaccharomyces pombe 972 |
S-adenosyl-L-homocysteine + [histone H4]-N6-methyl-L-lysine20 |
- |
? |
2.1.1.372 | S-adenosyl-L-methionine + [histone H4]-N6-methyl-L-lysine20 |
- |
Schizosaccharomyces pombe |
S-adenosyl-L-homocysteine + [histone H4]-N6,N6-dimethyl-L-lysine20 |
- |
? |
2.1.1.372 | S-adenosyl-L-methionine + [histone H4]-N6-methyl-L-lysine20 |
- |
Schizosaccharomyces pombe 972 |
S-adenosyl-L-homocysteine + [histone H4]-N6,N6-dimethyl-L-lysine20 |
- |
? |