EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
  2.1.1.371 | more |
Nsd3 is specific for the histones H3K4 and H3K27 residues |
Homo sapiens |
? |
- |
- |
| 2.1.1.371 | more |
enzyme shows versatility in substrate recognition. In a pan-methylation assay of histone H3, H3K4me3 and H3K27me3 species are preferably detected rather than me1 and me2 species, and H3K79-me1 and -me2 species are favored against me3 species. NSD3 shows significant di-/tri-methylation of histone H4K20 |
Homo sapiens |
? |
- |
- |
| 2.1.1.371 | more |
SET1 methylates both K9 and less efficiently K27 of histone H3 in vitro, reactions of EC 2.1.1.368 and 2.1.1.371, respectively |
Nicotiana tabacum |
? |
- |
- |
| 2.1.1.371 | S-adenosyl-L-methionine + a [histone H3]-L-lysine27 |
- |
Nicotiana tabacum |
S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine27 |
- |
? |
| 2.1.1.371 | S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine27 |
- |
Nicotiana tabacum |
S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine27 |
- |
? |
| 2.1.1.371 | S-adenosyl-L-methionine + [histone H3]-L-lysine27 |
- |
Homo sapiens |
S-adenosyl-L-homocysteine + [histone H3]-N6-methyl-L-lysine27 |
- |
? |
| 2.1.1.371 | S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine27 |
- |
Homo sapiens |
S-adenosyl-L-homocysteine + [histone H3]-N6,N6-dimethyl-L-lysine27 |
- |
? |
