EC Number   |
Substrates |
Organism |
Products  |
Reversibility |
|---|
   3.4.21.41 | acetyl-Gly-Lys-methyl ester + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | benzyloxycarbonyl-Gly-Arg-thiobenzyl ester + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | chordin + H2O |
C-terminal domains CUB1 and CUB2 are required for the ventralizing activity of Xld and for its ability to cleave chordin |
Xenopus laevis |
? |
- |
? |
| 3.4.21.41 | complement component C1s |
- |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | complement component C1s |
binding of C1 to activator is mediated by C1q and triggers activation of proenzyme C1r into an active protease C1rbar, which in turn activates C1s, thereby initiating the classical pathway of complement |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | complement component C1s |
regulation of the synthesis |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | complement component C1s |
activates the proenzyme form of C1s by limited proteolysis |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | more |
the ability of autoactivation of C1r and C1s cleavage activity is an inherent property of the SP domain |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | more |
the enzyme recognizes the a short collagen-like peptide containing the sequence Hyp-Gly-Lys-Leu-Gly-Pro |
Homo sapiens |
? |
- |
? |
| 3.4.21.41 | more |
the residues found in the activation loop of the zymogens capable of being activated by enzyme C1r play a major role in recognition of the active site of enzyme C1r |
Homo sapiens |
? |
- |
? |
