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<< < Results 11 - 20 of 72 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + L-cystathionine relative activity wild-type: 12% Mycobacterium tuberculosis ? - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + L-Lys relative activity wild-type: 7% Mycobacterium tuberculosis ? - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate - Bacillus subtilis ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate - Escherichia coli ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate - Lysinibacillus sphaericus ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate r Escherichia coli ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate r Bacillus cereus ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate specific for UDP-N-MurNAc-L-Ala-D-Glu and meso-2,6-diaminoheptanedioate Bacillus cereus ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate relative activity wild-type: 100% Mycobacterium tuberculosis ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
Show all pathways known for 6.3.2.13Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.13ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate the threedimensional structure of MurE from Mycobacterium leprae is modeled using comparative modeling methods based on the X-ray crystal structure of MurE from Escherichia coli. The docked complexes reveal the amino acids responsible for binding the substrates. Superposition of these complex structures suggests that carboxylic acid group of UDP-Nacetyl muramoyl-glycyl-D-glutamate is positioned in proximity to gamma-phosphate of the ATP to facilitate the formation of acylphosphate intermediate. The orientation of an amino group of meso-diaminopimelic acid facilitates the nucleophilic attack to form the product Mycobacterium leprae ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate - ?
<< < Results 11 - 20 of 72 > >>