EC Number   |
Substrates  |
Organism |
Products |
Reversibility |
|---|
   3.4.23.32 | more |
the enzyme is involved in protein degradation in wood destroying by the fungus |
Scytalidium lignicola |
? |
- |
? |
| 3.4.23.32 | more |
the enzyme shows preference for Phe and His over Leu, Ile, Val, Arg, and Lys. Peptides with positively charged amino acids Arg and Lys or aliphatic amino acids Leu, Ile, and Val are all poor substrates, 2-aminobenzoyl-KLIPSKQ-[N-(2,4-dinitrophenyl)-ethylenediamine], 2-aminobenzoyl-KLWPSKQ-[N-(2,4-dinitrophenyl)-ethylenediamine], 2-aminobenzoyl-KLVSSKQ-[N-(2,4-dinitrophenyl)-ethylenediamine], 2-aminobenzoyl-KLISSKQ-[N-(2,4-dinitrophenyl)-ethylenediamine], 2-aminobenzoyl-KLWSSKQ-[N-(2,4-dinitrophenyl)-ethylenediamine], and 2-aminobenzoyl-KLPSSKQ-[N-(2,4-dinitrophenyl)-ethylenediamine] are resistant to hydrolysis |
Scytalidium lignicola |
? |
- |
? |
| 3.4.23.32 | more |
the enzyme has a narrow substrate specificity, with preference for small, basic residues |
Scytalidium lignicola |
? |
- |
? |
| 3.4.23.32 | Oxidized insulin B-chain + H2O |
specifically hydrolyzes the Tyr26-Tyr27 bond, also hydrolyzes Glu13-Ala14, Ala14-Leu15, Phe24-Phe25, and less rapidly Tyr16-Leu17 and Glu21-Arg22 |
Scytalidium lignicola |
Hydrolyzed insulin B-chain |
- |
? |
| 3.4.23.32 | Oxidized insulin B-chain + H2O |
splits preferentially the Phe24-Phe25 bond at the rate 50% for total hydrolysis |
Ganoderma lucidum |
Hydrolyzed insulin B-chain |
- |
? |
| 3.4.23.32 | Proangiotensin + H2O |
rapid hydrolysis of His6-Pro7 bond, additional cleavage of the Tyr4-Ile5 bond |
Scytalidium lignicola |
? |
- |
? |
| 3.4.23.32 | Z-Phe-Xaa-Ala-Ala + H2O |
C-terminal cleavage site specificity, low activity |
Scytalidium lignicola |
Z-Phe + Xaa-Ala-Ala |
- |
? |
| 3.4.23.32 | Z-Xaa-Leu-Ala-Ala + H2O |
C-terminal cleavage site specificity, low activity |
Scytalidium lignicola |
Z-Xaa + Leu-Ala-Ala |
- |
? |
