EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    2.7.6.5 | guanosine 3'-diphosphate 5'-triphosphate + H2O |
- |
Mycobacterium tuberculosis ATCC 25618 |
GTP + diphosphate |
- |
? |
| 2.7.6.5 | more |
no substrate: 5'(beta,gamma-imino)triphosphate, 1,N6-ethyladenosine triphosphate, no diphosphate acceptors: ATP, UTP, CTP, dGTP, dGDP, 2'-O-methyl-GDP, 7-methyl-GDP |
Brevibacillus brevis |
? |
- |
? |
| 2.7.6.5 | more |
(p)ppGpp synthetase II is responsible for (p)ppGpp accumulation during carbon source downshift |
Geobacillus stearothermophilus |
? |
- |
? |
| 2.7.6.5 | more |
responsible for the synthesis of guanosine 3',5'-bisdiphosphate during stringent response to amino acid starvation |
Escherichia coli |
? |
- |
? |
| 2.7.6.5 | more |
the enzyme also possesses a potent Mn2+-dependent guanosine tetraphosphate hydrolysis activity, with complete hydrolysis to GDP and diphosphate |
Mycolicibacterium smegmatis |
? |
- |
? |
| 2.7.6.5 | more |
the enzyme transfers a diphosphate from ATP to GDP or GTP to synthesize guanosine 3'-diphosphate 5'-diphosphate (ppGpp) and guanosine 3'-diphosphate 5'-triphosphate (pppGpp), respectively. Enzyme RelMtb also encodes a second, distinct catalytic domain that hydrolyzes (p)ppGpp into diphosphate and GDP or GTP |
Mycobacterium tuberculosis |
? |
- |
? |
| 2.7.6.5 | more |
the enzyme is bifunctional showing synthase activity forming ppGpp and pppGpp, and hydrolase activity with the two compounds resulting in formation of GTP or GDP and diphosphate |
Bacillus subtilis |
? |
- |
? |
| 2.7.6.5 | more |
the enzyme is bifunctional showing synthase activity forming ppGpp and pppGpp, and hydrolase activity with the two compounds resulting in formation of GTP or GDP and diphosphate |
Bacillus subtilis 168 |
? |
- |
? |
| 2.7.6.5 | more |
the enzyme also possesses a potent Mn2+-dependent guanosine tetraphosphate hydrolysis activity, with complete hydrolysis to GDP and diphosphate |
Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 |
? |
- |
? |
| 2.7.6.5 | more |
the enzyme transfers a diphosphate from ATP to GDP or GTP to synthesize guanosine 3'-diphosphate 5'-diphosphate (ppGpp) and guanosine 3'-diphosphate 5'-triphosphate (pppGpp), respectively. Enzyme RelMtb also encodes a second, distinct catalytic domain that hydrolyzes (p)ppGpp into diphosphate and GDP or GTP |
Mycobacterium tuberculosis ATCC 25618 |
? |
- |
? |
