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<< < Results 11 - 20 of 74 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41more sirtuin6 performs H3K9 acetylation on histone H3, cf. EC 2.3.1.286 Homo sapiens ? - -
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41more a myristoyl peptide and a palmitoyl peptide are incubated with sirtuin6. Sirtuin6 exhibits both SIRT6 deacetylase and deacylase activities, cf. EC 2.3.1.286 Homo sapiens ? - -
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41more SIRT6 can undergo intramolecular mono-ADP-ribosylation utilizing NAD+ as a substrate, i.e. mono-ADP-ribosylation. SIRT6 also performs ADP-ribosyl transferase activity on other protein substrates, overview. Weak deacetylase activity of SIRT6 in vitro Homo sapiens ? - -
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41more SIRT6 can undergo intramolecular mono-ADP-ribosylation utilizing NAD+ as a substrate. Purified mouse SIRT6 successfully catalyzes the transfer of radiolabel from [32P]NAD+ onto itself, i.e. mono-ADP-ribosylation. also performs ADP-ribosyl transferase activity on other protein substrates, overview. Weak deacetylase activity of SIRT6 in vitro Mus musculus ? - -
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41more Sirt6-dependent deacetylation of H3K18 and H3K9 in a histone protein preparation and in HeLa nucleosomes Homo sapiens ? - -
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41NAD+ + Ac-AK(N6-acetyl)K-7-amido-4-methylcoumarin the substrate is based on the human tumour suppressor protein p53 Homo sapiens nicotinamide + Ac-AKK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41NAD+ + Ac-HK(N6-acetyl)K-7-amido-4-methylcoumarin the substrate is based on the human tumour suppressor protein p53 Homo sapiens nicotinamide + Ac-HKK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41NAD+ + Ac-RHK(N6-acetyl)K-7-amido-4-methylcoumarin the substrate is based on the amino acids 379-382 of the human tumour suppressor protein p53 Homo sapiens nicotinamide + Ac-RHKK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41NAD+ + Ac-RYQ(N6-acetyl)K-7-amido-4-methylcoumarin the peptide substrate mimics the biological deacetylation site of histone H3 K56 Homo sapiens nicotinamide + Ac-RYQK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41NAD+ + Ac-TAR(N6-acetyl)K-7-amido-4-methylcoumarin the peptide substrate mimics the biological deacetylation site of histone H3 K9 Homo sapiens nicotinamide + Ac-TARK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose - ?
<< < Results 11 - 20 of 74 > >>