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<< < Results 71 - 80 of 81 > >>
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.82,3-dihydrodipicolinate + NADH + H+ - Thermotoga maritima 2,3,4,5-tetrahydrodipicolinate + NAD+ + H2O - r
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.82,3-dihydrodipicolinate + NADH + H+ - Mycobacterium tuberculosis H37Rv 2,3,4,5-tetrahydrodipicolinate + NAD+ + H2O - r
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.82,3-dihydrodipicolinate + NADH + H+ - Thermotoga maritima MSB8 / DSM 3109 / ATCC 43589 2,3,4,5-tetrahydrodipicolinate + NAD+ + H2O - r
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.82,3-dihydrodipicolinate + reduced 3-acetylpyridine adenine dinucleotide - Escherichia coli 2,3,4,5-tetrahydrodipicolinate + oxidized 3-acetylpyridine adenine dinucleotide - ?
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.82,3-dihydrodipicolinate + reduced 3-acetylpyridine adenine dinucleotide - Escherichia coli 2,3,4,5-tetrahydrodipicolinate + oxidized 3-acetylpyridine adenine dinucleotide + H2O - r
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.82,3-dihydrodipicolinate + reduced nicotinamide hypoxanthine dinucleotide phosphate - Escherichia coli 2,3,4,5-tetrahydrodipicolinate + oxidized nicotinamide hypoxanthine dinucleotide phosphate + H2O - r
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.82,3-dihydrodipicolinate + thio-NADPH + H+ - Escherichia coli 2,3,4,5-tetrahydrodipicolinate + thio-NADP+ + H2O - r
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.8(4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate + NADPH + H+ - Escherichia coli ? - r
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.8more DHDPR accepts (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid as true substrate rather than dihydrodipicolinate, suggesting that DHDPR catalyzes an overall deoxygenation reaction, likely by a dehydratase-reductase route, substrate specificity, overview. A critical role is played by residue His 159 in the catalytic mechanism of DHDPR. Replacement of this residue with an alanine or a glutamine is reported to result in a 150-200fold reduction in catalytic rate as well as a 6fold increase in KM. His 159 has been proposed to act as a general acid during catalysis, providing the proton required after hydride addition. No activity with beta-hydroxypyruvate and 3-fluoropyruvate Escherichia coli ? - ?
Show all pathways known for 1.17.1.8Display the word mapDisplay the reaction diagram Show all sequences 1.17.1.8pyridine dicarboxylate + NADH + H+ stable substrate analog, 25 mM phosphate D2O (deuterium water) buffer, pH 7.8 for NMR analysis of binding interactions with saturation transfer difference titration studies at 298 K (25°C) Escherichia coli reduced pyridine dicarboxylate + NAD+ - ?
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