EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.10.3.16 | (1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylic acid + O2 |
- |
Burkholderia lata ATCC 17760 |
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylic acid + H2O2 |
- |
? |
1.10.3.16 | (1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylic acid + O2 |
- |
Pseudomonas fluorescens 2-79 |
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylic acid + H2O2 |
- |
? |
1.10.3.16 | more |
PhzG is the terminal enzyme in phenazine biosynthesis and its relaxed substrate specificity lets it participate in the generation of both phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid. Competition between flavin-dependent oxidations through PhzG and spontaneous oxidative decarboxylations determines the ratio of phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid and unsubstituted phenazine as the products of phenazine biosynthesis. PhzG synthesizes phenazines in their reduced form |
Pseudomonas fluorescens |
? |
- |
? |
1.10.3.16 | more |
PhzG is the terminal enzyme in phenazine biosynthesis and its relaxed substrate specificity lets it participate in the generation of both phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid. Competition between flavin-dependent oxidations through PhzG and spontaneous oxidative decarboxylations determines the ratio of phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid and unsubstituted phenazine as the products of phenazine biosynthesis. PhzG synthesizes phenazines in their reduced form |
Burkholderia lata |
? |
- |
? |
1.10.3.16 | more |
PhzG reacts with a non-aromatic tricyclic phenazine precursor to catalyze an oxidation/aromatization reaction that yields phenazine-1-carboxylate |
Pseudomonas fluorescens |
? |
- |
? |
1.10.3.16 | more |
PhzG reacts with a non-aromatic tricyclic phenazine precursor to catalyze an oxidation/aromatization reaction that yields phenazine-1-carboxylate |
Pseudomonas aeruginosa |
? |
- |
? |
1.10.3.16 | more |
PhzG is the terminal enzyme in phenazine biosynthesis and its relaxed substrate specificity lets it participate in the generation of both phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid. Competition between flavin-dependent oxidations through PhzG and spontaneous oxidative decarboxylations determines the ratio of phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid and unsubstituted phenazine as the products of phenazine biosynthesis. PhzG synthesizes phenazines in their reduced form |
Burkholderia lata ATCC 17760 |
? |
- |
? |
1.10.3.16 | more |
PhzG is the terminal enzyme in phenazine biosynthesis and its relaxed substrate specificity lets it participate in the generation of both phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid. Competition between flavin-dependent oxidations through PhzG and spontaneous oxidative decarboxylations determines the ratio of phenazine-1,6-dicarboxylic acid and phenazine-1-carboxylic acid and unsubstituted phenazine as the products of phenazine biosynthesis. PhzG synthesizes phenazines in their reduced form |
Pseudomonas fluorescens 2-79 |
? |
- |
? |