ATP + a protein
autophosphorylation at both Ser and Thr
ADP + a phosphoprotein
-
?
ATP + a protein
CHUK associates with the NF-kappaB inhibitory protein, IkappaB-alpha, in mammalian cells. CHUK specifically phosphorylates IkappaB-alpha on both Ser32 and Ser36, modifications that are required for targeted degradation of IkappaB-alpha via the ubiquitin-proteasome pathway
ADP + a phosphoprotein
-
?
ATP + a protein
the I kappa B/NF-kappa B system is a key determinant of mucosal inflammation and protection
ADP + a phosphoprotein
-
-
ATP + a protein
the I kappa B/NF-kappa B system is a key determinant of mucosal inflammation and protection
ADP + a phosphoprotein
-
-
ATP + a protein
the expression of pkn1 is developmentally regulated to start immediately before spore formation. The enzyme plays an important role in the onset of proper differentiation
ADP + a phosphoprotein
-
?
ATP + a protein
phosphorylation of IkappaBs marks them out for destruction, thereby relieving their inhibitory effect on NF-kappaB
ADP + a phosphoprotein
-
?
ATP + a protein
phosphorylates IkappaB inhibitory proteins, causing their degradation and activation of transcription factor NF-kappaB, a master activator of inflammatory responses
ADP + a phosphoprotein
-
?
ATP + a protein
phosphorylates IkappaB inhibitory proteins, causing their degradation and activation of transcription factor NF-kappaB, a master activator of inflammatory responses
ADP + a phosphoprotein
-
?
ATP + Bcl
phosphorylation at the C-terminus of Bcl by IKKbeta disrupts Bcl10/Malt1 association and Bcl10-mediated signaling
ADP + phosphorylated Bcl
-
?
ATP + Bcl
phosphorylation at the C-terminus of Bcl by IKKbeta disrupts Bcl10/Malt1 association and Bcl10-mediated signaling
ADP + phosphorylated Bcl
-
?