EC Number   |
Source Tissue |
Reference |
|---|
   3.4.21.6 | artery |
middle cerebral |
651191 |
| 3.4.21.6 | atrial tissue |
- |
731756 |
| 3.4.21.6 | blood |
- |
650933, 651123, 651189, 651191, 653059, 81426 |
| 3.4.21.6 | blood |
factor Xa is part of the prothrombinase complex formed by factor Xa, nonenzymatic cofacor Va and Ca2+ on the phospholipid surface of platelets or endothelial cells |
652731 |
| 3.4.21.6 | blood clot |
bound to |
650933 |
| 3.4.21.6 | blood plasma |
- |
666180, 695438, 698769, 699159, 708505, 709730, 710601, 710609, 732376, 752614, 754844, 81416, 81419, 81423 |
| 3.4.21.6 | blood platelet |
- |
731536 |
| 3.4.21.6 | blood platelet |
coagulation factors from plasma bind to tissue factor TF-expressing cells, e.g. lung fibroblast, become activated, dissociate, and diffuse into plasma to form enzymatic complexes on the membranes of activated platelets, overview |
683259 |
| 3.4.21.6 | blood vessel wall |
- |
717829 |
| 3.4.21.6 | C2C12 cell |
enzyme elicits a signaling response. ERK1/2 phosphorylation by factor Xa is dependent on protease-activated receptor PAR-2 cleavage and leads to fibroblast proliferation, migration, and differentiation into myofibroblasts |
701355 |
