EC Number   |
General Information |
Reference  |
|---|
   7.1.1.7 | physiological function |
inactivation of cydA or cydB by gene disruption results in loss of d-heme absorbance at 631 nm. Inactivation of cydA has no effect on the ability of Mycobacterium smegmatis to exit from stationary phase at 37 or 42°C. No discernible growth defect of the mutant is observed under moderately aerobic conditions, while the mutant displays a significant growth disadvantage when cocultured with the wild type under extreme microaerophilia. The cydA mutant displays a competitive growth disadvantage in the presence of the terminal oxidase inhibitor, cyanide, when cocultured with wild type at 21% air saturation in an oxystat |
727738 |
| 7.1.1.7 | physiological function |
inactivation of cydA or cydB gene disruption results in loss of d-heme absorbance at 631 nm |
727738 |
| 7.1.1.7 | physiological function |
the expression of cytochrome bd enhances bacterial tolerance to nitrosative stress |
741957 |
| 7.1.1.7 | physiological function |
the enzyme contributes to bacterial resistance to nitric oxide and hydrogen peroxide |
741966 |
| 7.1.1.7 | physiological function |
induction of cytochrome bd helps Salmonella grow and respire in the presence of inhibitory nitric oxide |
743207 |
| 7.1.1.7 | physiological function |
when cystine is provided and sulfide levels rise, Escherichia coli becomes strictly dependent upon cytochrome bd oxidase for continued respiration. Low-micromolar levels of sulfide inhibit the proton-pumping cytochrome bo oxidase. In the absence of the back-up cytochrome bd oxidase, growth fails. Exogenous sulfide elicits the same effect |
743301 |
| 7.1.1.7 | physiological function |
the interheme electron backflow reaction induced by photodissociation of CO from heme d in one-electron reduced cytochrome bd-I comprises two kinetically different phases: the fast electron transfer from heme d to heme b595 within 0.2-1.5 micros and the slower electron equilibration with tau of about 16 micros. At 200 ns, there is no electron transfer |
743604 |
| 7.1.1.7 | physiological function |
the enzyme is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress |
-, 743792 |
| 7.1.1.7 | physiological function |
loss of the flavohemoglobin Hmp and cytochrome bd-I elicit high sensitivity to NO-mediated growth inhibition. The subunits cydAB mutant displays an attenuated colonisation phenotype in a mouse model after 2 days |
743822 |
| 7.1.1.7 | physiological function |
the enzyme contributes to Escherichia coli survival in the mouse bladder |
-, 743822 |
