EC Number   |
General Information |
Reference |
|---|
  3.1.15.B1 | evolution |
RNase D (EC 3.1.13.5) is a 3' to 5' hydrolytic exoribonuclease belonging to the DEDDy family. In contrast to RNase D, which degrades both single-stranded RNA (ssRNA) and double-stranded RNA (dsRNA), Agrobacterium tumefaciens NrnC hydrolyses ssRNA, single-stranded DNA (ssDNA), and double-stranded DNA (dsDNA) with high efficiency but does not degrade dsRNA |
-, 750652 |
| 3.1.15.B1 | more |
enzyme At_NrnC forms an octameric hollow cylindrical structure that allows ssRNA, ssDNA, and dsDNA, but not dsRNA, to enter the central tunnel where the multiple active sites perform hydrolysis, active site structure of At_NrnC, overview |
-, 750652 |
| 3.1.15.B1 | physiological function |
NrnC is an RNase D-like protein from Agrobacterium, it is an octameric nuclease. In contrast to RNase D (EC 3.1.13.5), which degrades both single-stranded RNA (ssRNA) and double-stranded RNA (dsRNA), Agrobacterium tumefaciens NrnC hydrolyses ssRNA, single-stranded DNA (ssDNA), and double-stranded DNA (dsDNA) with high efficiency but does not degrade dsRNA |
-, 750652 |
