EC Number   |
General Information |
Reference |
|---|
   2.7.3.4 | evolution |
the enzyme belongs to the highly conserved phosphagen (PK) kinase family of enzymes. The polypeptide is homologous to taurocyamine kinase (TK) of the invertebrate animals and consists of two contiguous domains. Clonorchis sinensis CsTK gene consists of 13 exons intercalated with 12 introns. This suggests an evolutionary pathway originating from an arginine kinase gene group, and distinguishes annelid taurocyamine kinase from the general creatine kinase phylogenetic group |
739402 |
| 2.7.3.4 | evolution |
the enzyme belongs to the phosphagen kinase (PK) family. Schistosoma mansoni taurocyamine SmTK is derived from gene duplication, as are all known trematode taurocyamine kinases |
738646 |
| 2.7.3.4 | evolution |
the enzyme belongs to the phosphagen kinases family of enzymes. Phylogenetic analysis of oomycete enzymes, overview |
-, 738077 |
| 2.7.3.4 | more |
the residues Y84 and Y87 of domains 1 and 2, respetively are required for catalytic activity, while the residues A59 and A62 in the GS region of domains 1 and 2, respectively, have a key role in substrate binding |
738180 |
| 2.7.3.4 | physiological function |
within animal species, these enzymes play a critical role in energy homeostasis by catalyzing the reversible transfer of a high-energy phosphoryl group from Mg-ATP to an acceptor molecule containing a guanidinium group |
-, 738077 |
