EC Number   |
General Information |
Reference |
|---|
    2.5.1.96 | malfunction |
a mutant of squalene synthase is converted to a dehydrosqualene synthase, the various mutations are lustered around the residues that are proposed to be important for NADPH binding |
738235 |
| 2.5.1.96 | metabolism |
Bacillus firmus synthesizes C30 carotenoids via farnesyl pyrophosphate, forming apophytoene as the first committed step in the pathway. The products of the pathway is methyl 4'-[(6-O-acyl-glycosyl)oxy]-4,4'-diapolycopen-4-oic acid and 4,4'-diapolycopen-4,4'-dioic acid with putative glycosyl esters |
-, 739019 |
| 2.5.1.96 | metabolism |
Bacillus indicus synthesizes C30 carotenoids via farnesyl pyrophosphate, forming apophytoene as the first committed step in the pathway. The products of the pathway is methyl 4'-[(6-O-acyl-glycosyl)oxy]-4,4'-diapolycopen-4-oic acid and 4,4'-diapolycopen-4,4'-dioic acid with putative glycosyl esters |
-, 739019 |
| 2.5.1.96 | physiological function |
the biosynthesis of 4,4'-diaponeurosporene starts with the condensation of two molecules of farnesyl diphosphate by dehydrosqualene synthase CrtM, the reaction product of this enzyme is dehydrosqualene and not squalene. Dehydrosqualene, i.e.4,4'-diapophytoene, is successively dehydrogenated by desaturase CrtN to form the yellow main intermediate 4,4'-diaponeurosporene |
-, 715332 |
