EC Number   |
General Information |
Reference  |
|---|
   1.14.11.9 | metabolism |
part of flavonoid biosynthetic pathway |
701213 |
| 1.14.11.9 | metabolism |
the enzyme is involved in the flavonoid and phenylpropanoid biosynthesis pathway, overview |
-, 713238 |
| 1.14.11.9 | metabolism |
flavanone 3-hydroxylase converts flavanones to dihydroflavonols for anthocyanin biosynthesis |
713256 |
| 1.14.11.9 | more |
in Sorghum seedlings, expression of the two F3H genes is either absent or strongly suppressed during the accumulation of 3-deoxyanthocyanidins |
713256 |
| 1.14.11.9 | physiological function |
flavanone 3-hydroxylase converts flavanones to dihydroflavonols for anthocyanin biosynthesis, F3H is a key flavonoid structural gene |
713256 |
| 1.14.11.9 | evolution |
the F3H isozymes have a unique motif of pfam03171 that is maintained in the superfamily of 2-oxoglutarate and Fe(II)-dependent oxygenases |
725165 |
| 1.14.11.9 | metabolism |
flavanone 3-hydroxylase is a key enzyme at a diverging point of the flavonoid pathway leading to production of different pigments: phlobaphene, proanthocyanidin, and anthocyanin, flavonoid biosynthetic pathway, overview |
725165 |
| 1.14.11.9 | physiological function |
the enzyme is involved in the red pigmentation of grain tissues, overview |
725165 |
| 1.14.11.9 | evolution |
the enzyme belongs to the 2-oxoglutarate-dependant dioxygenases |
726200 |
| 1.14.11.9 | malfunction |
silencing of flavanone-3-hydroxylase leads to an accumulation of flavanones in leaves, but in contrast not to the formation of 3-deoxyflavonoids. In prohexadione-Ca treated leaves the 3-deoxyflavonoid luteoforol is formed from accumulating flavanones, acting as an antimicrobial compound against the fire blight pathogen Erwinia amylovora. Inducible resistance to fire blight by prohexadione-Ca is not observed with the antisense flavanone-3-hydroxylase apple plants |
726200 |
