EC Number |
General Information |
Reference |
---|
1.13.11.55 | evolution |
the enzyme belongs to the SOR protein family, phylogenetic analysis, overview |
-, 725278 |
1.13.11.55 | metabolism |
proposed sulfur metabolism pathways of Sulfobacillus acidophilus strain TPY involving the enzyme, overview |
-, 742580 |
1.13.11.55 | metabolism |
sulfur oxygenase reductase is the initial enzyme of the sulfur oxidation pathway in the thermoacidophilic Archaeon Acidianus ambivalens catalyzing an oxygen-dependent sulfur disproportionation to H2S, sulfite and thiosulfate |
725074 |
1.13.11.55 | metabolism |
the enzyme is involved in the sulfur oxidation metabolism of Acidithiobacillus thiooxidans strain A01, sulfur oxidation model, overview |
-, 742198 |
1.13.11.55 | more |
modeling of the sulfur oxidation system in Acidithiobacillus caldus , overview |
-, 726299 |
1.13.11.55 | more |
the spherical, hollow, cytoplasmic enzyme is composed of 24 identical subunits with an active site pocket each comprising a mononuclear non-heme iron site and a cysteine persulfide. Substrate access and product exit occur via apolar chimney-like protrusions at the fourfold symmetry axes, via narrow polar pores at the threefold symmetry axes and via narrow apolar pores within in each subunit. The expansion of the pores in the outer shell leads to an increased enzyme activity while the integrity of the active site pore seems to be important. The iron site and the three conserved cysteine residues are located in an active site pocket that is connected to the inner cavity of the sphere by a narrow pore formed by two adjacent methionines and a phenylalanine. Modeling of the SOR and its pores, overview. Opening the putative substrate and product pathways in the outer shell leads to a significant increase in specific activity and to a shift in the stoichiometry of the products |
725074 |
1.13.11.55 | more |
three-dimensional modeling of the enzyme, overview |
-, 725278 |
1.13.11.55 | physiological function |
catalyzes the initial step in the dissimilatory sulfur oxidation pathway |
723994 |
1.13.11.55 | physiological function |
initial enzyme in the aerobic sulfur metabolism of the thermoacidophilic and chemolithoautotrophic crenarchaeote Acidianus ambivalens |
-, 664199 |
1.13.11.55 | physiological function |
initial enzyme in the sulfur-oxidation pathway |
-, 724213 |