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7.6.2.9
physiological function
Vibrio anguillarum possesses a putative glycine betaine synthesis system, which is encoded by betABI and synthesizes glycine betaine from its precursor choline. Significant upregulation of the bet gene at the transcriptional level is noted in log phase in response to cold-stress. The accumulation of betaine glycine is only appearing at low growth temperatures, suggesting that response regulation of both synthesis system and transporter system are cold-dependent. Two putative ABC transporters and three putative BCCT family transporters are associated with glycine betaine uptake. Glycine betaine serves as an effective cold stress protectant, thus the enzyme complex is involved in cold adaptation of Vibrio anguillarum via regulation of the glycine betaine level
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