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EC Number General Information Commentary Reference
Show all pathways known for 5.4.3.10Display the word mapDisplay the reaction diagram Show all sequences 5.4.3.10more the stereochemistry of the PAM-catalyzed reaction originates from the enzyme's ability to bind trans-cinnamic acid in two different orientations, with either the si,si face or the re,re face directed toward the MIO group, as evidenced by two distinct carboxylate binding modes. The N231 side chain promotes prosthetic MIO group formation by increasing the nucleophilicity of the G177 N atom through acidification of the amide proton. PAM enzyme structures comparisons, overview 747670
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