EC Number   |
General Information |
Reference |
|---|
    2.2.1.6 | physiological function |
deletion of gene ilv2 encoding acetolactate synthase results in loss of viability during isoleucine and valine starvation due to 2-oxobutanoate accumulation. Rapamycin further decreases vialbility of the mutant. Recovery from starvation is influenced by the carbon source present during recovery |
700065 |
| 2.2.1.6 | physiological function |
deletion of gene ilv2 encoding acetolactate synthase results in significant attenuation of virulence and a grater than 100fold reduction in viability after only four hours of isoleucine and valine starvation due to 2-oxobutanoate accumulation. Rapamycin increases vialbility of both ilv1 and ilv2 mutants. Recovery from starvation is influenced by the carbon source present during starvation |
700065 |
| 2.2.1.6 | physiological function |
MoIlv2 plays a crucial role in isoleucine and valine biosynthesis, whereas MoIlv6 contributes to isoleucine and leucine biosynthesis, both genes are required for fungal pathogenicity. MoIlv2 and MoIlv6 play a critical role in maintaining the balance of intracellular amino acid levels. And MoIlv2 and MoIlv6 are involved in aerial hyphal growth, pigmentation, conidial morphogenesis and pathogenicity on rice and barley |
-, 734734 |
| 2.2.1.6 | physiological function |
Pyrococcus furiosus produces acetoin as amajor end product at growth temperatures below 85°C in a temperature-dependent manner via a acetolactate synthase whose gene expression and biochemical function are temperature-dependent |
734625 |
| 2.2.1.6 | physiological function |
the enzyme contributes to pH homeostasis in acid stress conditions |
-, 733995 |
| 2.2.1.6 | physiological function |
the enzyme is involved in the production of acetoin (3-hydroxybutanone) as a major product at growth temperatures below 80°C. Acetoin is produced by wild-type Pyrococcus furiosus during growth at sub-optimal temperatures below 80°C |
734625 |
| 2.2.1.6 | physiological function |
the enzyme plays a critical role in maintaining the balance of intracellular amino acid level, is involved in aerial hyphal growth, pigmentation, conidial morphogenesis, and is required for fungal pathogenicity |
-, 734734 |
| 2.2.1.6 | physiological function |
transformation of a H+-ATPase defective strain with a C-terminal truncation of acetohydroxyacid synthase gene ilvBN results in increased valine production from 21.7 mM for wild-type to 46.7 mM and increase in the valine intermediate acetoin. Inserting acetohydroxyacid isomeroreductase gene into the ilvBN plasmid further increases valine producion |
696827 |
