EC Number   |
Expression |
Reference |
|---|
    5.3.99.5 | more |
4 weeks of streptozotocin-induced diabetes do not increase the retinal levels of TxS |
703587 |
| 5.3.99.5 | more |
inhibition of platelet TXA2 generation (acetylsalicylic acid), lowering of cholesterol (statins), inhibition of platelet aggregation (clopidogrel), or promoting vasodilatation (dipyridamole) has no effect on TXAS mRNA expression levels |
705219 |
| 5.3.99.5 | up |
after 8 and 16 weeks on the fat diet, aortic arches from low-density lipoprotein receptor deficient mice show a significant increase in TXAS mRNA level when compared with control |
701992 |
| 5.3.99.5 | up |
an overall increase in TXS expression is observed in tumor tissues relative to normal, increased TXS expression at mRNA level is reported in renal cell carcinoma, breast carcinoma, prostate cancer and uterine cancer when compared with matched normal tissues |
702474 |
| 5.3.99.5 | up |
smokers tend to express more TxAS than nonsmokers |
701976 |
| 5.3.99.5 | up |
TNF-alpha, U46619 and 8-isoprostane F2alpha and hypoxia all augment TXAS protein expression. NADPH oxidase-1 (but not NADPH oxidase-4) gene silencing, as well as picotamide and iloprost inhibit the increase in TXAS expression and activity |
714914 |
| 5.3.99.5 | up |
TXAS increases in atherosclerotic lesions of patients with recent symptoms of thrombotic events |
705219 |
| 5.3.99.5 | up |
TXAS mRNA expression is increased within the vascular wall in mouse models of atherosclerosis with advanced lesions |
705219 |
| 5.3.99.5 | up |
TXSA is upregulated in human glial tumors |
706861 |
