EC Number   |
Expression |
Reference |
|---|
   3.6.4.B10 | down |
role of AKT in regulating TCP1 downstream of FGFR2, Akt inhibition results in downregulation of TCP1 protein as well as reduced levels of Akt and RPS6 phosphorylation |
756668 |
| 3.6.4.B10 | more |
expression of CCT is not induced by stress conditions |
758147 |
| 3.6.4.B10 | more |
subunit CCT1 is transcriptionally modulated by the driver oncogene, phosphatidylinositide 3-kinases (PI3K) |
756984 |
| 3.6.4.B10 | up |
cardiac-specific upregulation of CCT components under time restricted feeding (TRF) |
756722 |
| 3.6.4.B10 | up |
induced when halophilic cells are exposed to a low salt stress |
727833 |
| 3.6.4.B10 | up |
possesses two chaperonins, cold-inducible CpkA and heat-inducible CpkB, which are involved in adaptation to low and high temperatures, respectively |
-, 734095 |
| 3.6.4.B10 | up |
the TCP1 subunit of TRiC is regulated by fibroblast growth factor receptor 2 (FGFR2), the induction of TCP1 by FGFR2 is inhibited by PD173074, i.e. N-[2-[[4-(diethylamino)butyl]amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea], an ATP-competitive inhibitor. FGFR2 signals through PI3K and Akt to regulate TCP1 expression |
756668 |
