EC Number   |
Expression |
Reference |
|---|
    1.4.3.4 | down |
a knockdown of SRY expression substantially reduces both MAO A 2- and 0.24-kb core-promoter activities to below 40% in the transfected cells, overview. R1, i.e. RAM2/CDCA7L/JPO2, a transcription repressor, downregulates MAO A gene expression by competing with Sp1 for binding to Sp1 sites |
703615 |
| 1.4.3.4 | down |
microRNA-142 reduces monoamine oxidase A expression and activity in neuronal cells by downregulating SIRT1 |
743640 |
| 1.4.3.4 | down |
Ni2+ and Pb2+ reduce the expression of MAO in brain after exposure over 24 h and 72 h, overview |
703488 |
| 1.4.3.4 | up |
enzyme activity increases up to day 3 after germination, thereafter decreasing again |
723891 |
| 1.4.3.4 | up |
Ni2+ and Pb2+ induce the expression of MAO in brain after exposure over 24 h, but the expression level is normalized after 72 h, overview |
703488 |
| 1.4.3.4 | up |
stable overexpression of SRY in the BE(2)C cell line results in ibncreased MAO-A mRNA and catalytic activity levels, SRY increases MAO A-promoter activity up to 6fold in a concentration-dependent manner, overview. Sp1 synergistically enhances the SRY binding to and activation of the MAO A promoter by interacting and forming a transcriptional regulatory complex with SRY at the MAO A core promoter in vivo, Sp4 activates the MAO A core promoter as Sp1. Sp3 represses this activation by competing with Sp1 and Sp4 |
703615 |
