EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
3.4.24.B10 | 667133 |
ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor |
Am. J. Pathol. |
165 |
1743-1753 |
2004 |
Homo sapiens |
15509542 |
3.4.24.B10 | 677449 |
Transgenic overexpression of ADAM12 suppresses muscle regeneration and aggravates dystrophy in aged mdx mice |
Am. J. Pathol. |
171 |
1599-1607 |
2007 |
Mus musculus |
17982130 |
3.4.24.B10 | 690386 |
Role of a disintegrin and metalloprotease-12 in neutrophil recruitment induced by airway epithelium |
Am. J. Respir. Cell Mol. Biol. |
41 |
449-458 |
2009 |
Homo sapiens |
19213876 |
3.4.24.B10 | 733079 |
A substrate-optimized electrophoretic mobility shift assay for ADAM12 |
Anal. Biochem. |
452 |
34-42 |
2014 |
Homo sapiens |
24534253 |
3.4.24.B10 | 677883 |
ADAM-12 (meltrin alpha) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage |
Arthritis Rheum. |
58 |
778-789 |
2008 |
Homo sapiens |
18311789 |
3.4.24.B10 | 649557 |
ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3 |
Biochem. Biophys. Res. Commun. |
278 |
511-515 |
2000 |
Homo sapiens |
11095942 |
3.4.24.B10 | 649712 |
Metalloprotease-disintegrin ADAM 12 interacts with alpha-actinin-1 |
Biochem. J. |
357 |
353-361 |
2001 |
Mus musculus |
11439084 |
3.4.24.B10 | 711148 |
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2) |
Biochem. J. |
430 |
79-86 |
2010 |
Homo sapiens |
20533908 |
3.4.24.B10 | 678344 |
Catalytic properties of ADAM12 and its domain deletion mutants |
Biochemistry |
47 |
537-547 |
2008 |
Homo sapiens |
18081311 |
3.4.24.B10 | 667947 |
Structure-based virtual screening and biological evaluation of potent and selective ADAM12 inhibitors |
Bioorg. Med. Chem. Lett. |
14 |
6071-6074 |
2004 |
Homo sapiens |
15546732 |