EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   3.4.23.39 | 753556 |
Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights |
FEBS J. |
285 |
3077-3096 |
2018 |
Plasmodium falciparum |
29943906 |
| 3.4.23.39 | 754374 |
Fighting malaria structureguided discovery of nonpeptidomimetic plasmepsin inhibitors |
J. Med. Chem. |
58 |
5151-5163 |
2015 |
Plasmodium falciparum |
25719272 |
| 3.4.23.39 | 755345 |
Flap flexibility amongst plasmepsins I, II, III, IV, and V Sequence, structural, and molecular dynamics analyses |
Proteins |
83 |
1693-1705 |
2015 |
Plasmodium falciparum |
26146842 |
| 3.4.23.39 | 754378 |
Fragment-based discovery of 2-aminoquinazolin-4(3H)-ones as novel class nonpeptidomimetic inhibitors of the plasmepsins I, II, and IV |
J. Med. Chem. |
59 |
374-387 |
2016 |
Plasmodium falciparum |
26670264 |
| 3.4.23.39 | 755103 |
Hydroxyethylamine based phthalimides as new class of plasmepsin hits design, synthesis and antimalarial evaluation |
PLoS ONE |
10 |
e0139347 |
2015 |
Plasmodium falciparum |
26502278 |
| 3.4.23.39 | 752622 |
In silico docking roselle (Hibiscus sabdariffa L.) calyces flavonoids as antimalarial against plasmepsin 1 and plasmepsin 2 |
Asian J. Pharm. Clin. Res. |
10. |
183 |
2017 |
Plasmodium falciparum |
- |
| 3.4.23.39 | 753935 |
Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine |
Int. J. Parasitol. Drugs Drug Resist. |
9 |
16-22 |
2019 |
Plasmodium falciparum |
30580023 |
| 3.4.23.39 | 669987 |
A heterogeneous enzymatic assay for quantification of plasmepsin II activity and the evaluation of its inhibitors |
J. Pharm. Biomed. Anal. |
34 |
833-840 |
2004 |
Plasmodium falciparum |
15019062 |
| 3.4.23.39 | 679228 |
Achiral, cheap, and potent inhibitors of plasmepsins I, II, and IV |
ChemMedChem |
1 |
1341-1345 |
2006 |
Plasmodium falciparum |
17091526 |
| 3.4.23.39 | 648187 |
Active Site Contribution to Specificity of the Aspartic Proteases Plasmepsins I and II |
J. Biol. Chem. |
277 |
41009-41013 |
2002 |
Plasmodium falciparum |
12189138 |
