EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
3.4.21.B25 | 753276 |
Novel insights into structure-activity relationships of N-terminally modified PACE4 inhibitors |
ChemMedChem |
11 |
289-301 |
2016 |
Homo sapiens |
26751825 |
3.4.21.B25 | 754757 |
PACE4 regulates proliferation, migration and invasion in human breast cancer MDA-MB-231 cells |
Mol. Med. Rep. |
11 |
698-704 |
2015 |
Homo sapiens |
25333574 |
3.4.21.B25 | 753278 |
Rational design of a highly potent and selective peptide inhibitor of PACE4 by salt bridge interaction with D160 at position P3 |
ChemMedChem |
12 |
1169-1172 |
2017 |
Homo sapiens |
28722823 |
3.4.21.B25 | 754759 |
PACE4 regulates apoptosis in human pancreatic cancer Panc-1 cells via the mitochondrial signaling pathway |
Mol. Med. Rep. |
14 |
5205-5210 |
2016 |
Homo sapiens |
27779720 |
3.4.21.B25 | 754231 |
PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation |
J. Cell Biol. |
210 |
1185-1197 |
2015 |
Mus musculus |
26416966 |
3.4.21.B25 | 754509 |
Expression of paired basic amino acid-cleaving enzyme 4 (PACE4) correlated with prognosis in non-small cell lung cancer (NSCLC) patients |
J. Thorac. Dis. |
7 |
850-860 |
2015 |
Homo sapiens |
26101640 |
3.4.21.B25 | 753401 |
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways |
Drug Des. Devel. Ther. |
9 |
5911-5923 |
2015 |
Homo sapiens |
26604689 |
3.4.21.B25 | 651744 |
A novel human PACE4 isoform, PACE4E is an active processing protease containing a hydrophobic cluster at the carboxy terminus |
J. Biochem. |
121 |
941-948 |
1997 |
Homo sapiens |
9192737 |
3.4.21.B25 | 651760 |
Subtilisin-like proprotein convertases, PACE4 and PC8, as well as furin, are endogenous proalbumin convertases in HepG2 cells |
J. Biochem. |
125 |
627-633 |
1999 |
Homo sapiens |
10050053 |
3.4.21.B25 | 673252 |
XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFb proteins in Xenopus development |
Development |
132 |
591-602 |
2005 |
Xenopus laevis |
15634697 |