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Results 1 - 10 of 69 > >>
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EC Number BRENDA No. Title Journal Volume Pages Year Organism PubMed ID
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22752982 Development of a novel tricyclic class of potent and selective FIXa inhibitors Bioorg. Med. Chem. Lett. 25 5437-5443 2015 Homo sapiens 26318999
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22752991 Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors Bioorg. Med. Chem. Lett. 27 2622-2628 2017 Homo sapiens 28408226
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22753894 Emicizumab, a humanized bispecific antibody to coagulation factors IXa and X with a factor VIIIa-cofactor activity Int. J. Hematol. 111 20-30 2018 Homo sapiens 30350119
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22755584 Expression and characterization of a novel human recombinant factor IX molecule with enhanced in vitro and in vivo clotting activity Thromb. Res. 135 1017-1024 2015 Homo sapiens 25795563
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22752714 Releasing the brakes in coagulation factor IXa by co-operative maturation of the substrate-binding site Biochem. J. 473 2395-2411 2016 Homo sapiens 27208168
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22667957 5-Amidinobenzo[b]thiophenes as dual inhibitors of factors IXa and Xa Bioorg. Med. Chem. Lett. 15 29-35 2005 Homo sapiens 15582405
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22667946 5-Amidinoindoles as dual inhibitors of coagulation factors IXa and Xa Bioorg. Med. Chem. Lett. 14 5269-5273 2004 Homo sapiens 15454209
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22732075 A sequential mechanism for exosite-mediated factor IX activation by factor XIa J. Biol. Chem. 287 38200-38209 2012 Homo sapiens 22961984
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22717103 A study of the expression of functional human coagulation factor IX in keratinocytes using a nonviral vector regulated by K14 promoter Appl. Biochem. Biotechnol. 162 1599-1611 2010 Homo sapiens 20397061
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.22732114 A3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IX J. Biol. Chem. 288 26105-26111 2013 Homo sapiens 23884417
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