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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
3.2.1.166
753249
Design, synthesis, and evaluation of heparan sulfate mimicking glycopolymers for inhibiting heparanase activity
Chem. Commun. (Camb.)
53
9163-9166
2017
Homo sapiens
28766595
3.2.1.166
753154
Development of new methods for determining the heparanase enzymatic activity
Carbohydr. Res.
412
66-70
2015
Homo sapiens
26062789
3.2.1.166
754818
Functional and structural characterization of a heparanase
Nat. Chem. Biol.
11
955-957
2015
Burkholderia pseudomallei
26565989
3.2.1.166
759360
Heparan sulfate biosynthetic system is inhibited in human glioma due to EXT1/2 and HS6ST1/2 down-regulation
Int. J. Mol. Sci.
18
2301
2017
Homo sapiens
29104277
3.2.1.166
753404
Heparanase from basic research to therapeutic applications in cancer and inflammation
Drug Resist. Updat.
29
54-75
2016
Homo sapiens
27912844
3.2.1.166
755125
Heparanase activates antithrombin through the binding to its heparin binding site
PLoS ONE
11
e0157834
2016
Homo sapiens
27322195
3.2.1.166
755259
Heparanase is required for activation and function of macrophages
Proc. Natl. Acad. Sci. USA
113
E7808-E7817
2016
Mus musculus
27849593
3.2.1.166
754394
Novel symmetrical benzazolyl derivatives endowed with potent anti-heparanase activity
J. Med. Chem.
61
10834-10859
2018
Homo sapiens
30412404
3.2.1.166
754873
Structural characterization of human heparanase reveals insights into substrate recognition
Nat. Struct. Mol. Biol.
22
1016-1022
2015
Homo sapiens
26575439
3.2.1.166
731254
1H NMR spectroscopic studies establish that heparanase is a retaining glycosidase
Biochem. Biophys. Res. Commun.
443
185-188
2014
Homo sapiens
24291708
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