EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages  |
Year |
Organism |
PubMed ID |
|---|
   3.4.21.41 | 752432 |
Periodontal Ehlers-Danlos syndrome is caused by mutations in C1R and C1S, which encode subcomponents C1r and C1s of complement |
Am. J. Hum. Genet. |
99 |
1005-1014 |
2016 |
Homo sapiens |
27745832 |
| 3.4.21.41 | 753085 |
Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics |
BMC Biotechnol. |
18 |
15 |
2018 |
Homo sapiens |
29544494 |
| 3.4.21.41 | 753377 |
Molecular features and the transcriptional and functional delineation of complement system activators C1r and C1s from Sebastes schlegelii |
Dev. Comp. Immunol. |
81 |
279-290 |
2018 |
Sebastes schlegelii |
29247723 |
| 3.4.21.41 | 753598 |
Characterization of rock bream (Oplegnathus fasciatus) complement components C1r and C1s in terms of molecular aspects, genomic modulation, and immune responsive transcriptional profiles following bacterial and viral pathogen exposure |
Fish Shellfish Immunol. |
46 |
656-668 |
2015 |
Oplegnathus fasciatus |
26241508 |
| 3.4.21.41 | 755267 |
Structure of the C1r-C1s interaction of the C1 complex of complement activation |
Proc. Natl. Acad. Sci. USA |
115 |
768-773 |
2018 |
Homo sapiens |
29311313 |
| 3.4.21.41 | 81401 |
Protein engineering studies on C1r and C1s |
Behring Inst. Mitt. |
93 |
103-114 |
1993 |
Homo sapiens |
8172556 |
| 3.4.21.41 | 81405 |
One active C1r subunit is sufficient for the activity of the complement C1 complex: stabilization of C1r in the zymogen form by point mutations |
J. Immunol. |
162 |
1108-1112 |
1999 |
Homo sapiens |
9916740 |
| 3.4.21.41 | 81398 |
Purified proenzyme C1r. Some characteristics of its activation and subsequent proteolytic cleavage |
Biochim. Biophys. Acta |
616 |
116-129 |
1980 |
Homo sapiens |
6254570 |
| 3.4.21.41 | 81400 |
Regulation of synthesis of complement proteins in HEp2 cells |
Clin. Immunol. Immunopathol. |
67 |
117-123 |
1993 |
Homo sapiens |
8519088 |
| 3.4.21.41 | 717786 |
Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r |
J. Biol. Chem. |
285 |
11863-11869 |
2010 |
Homo sapiens |
20178990 |
