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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
2.3.1.B41
729362
Oxidative stress induces endothelial cell senescence via downregulation of Sirt6
Biomed Res. Int.
2014
902842
2014
Homo sapiens
25162034
2.3.1.B41
738283
Posttranslational modification of Sirt6 activity by peroxynitrite
Free Radic. Biol. Med.
79
176-185
2015
Homo sapiens
25476852
2.3.1.B41
739158
SIRT6 deacetylates H3K18Ac at pericentric chromatin to prevent mitotic errors and cellular senescence
Nat. Struct. Mol. Biol.
23
434-440
2016
Homo sapiens
27043296
2.3.1.B41
730498
SIRT6 exhibits nucleosome-dependent deacetylase activity
Nucleic Acids Res.
41
8537-8545
2013
Homo sapiens
23892288
2.3.1.B41
730790
SIRT6 is required for normal retinal function
PLoS One
9
e98831
2014
Homo sapiens
24896097
2.3.1.B41
729520
SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer
Cancer Res.
74
5925-5933
2014
Homo sapiens
25320180
2.3.1.B41
730464
SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine
Nature
496
110-113
2013
Homo sapiens
23552949
2.3.1.B41
737977
Sirtuin 6 promotes transforming growth factor-beta1/H2O2/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence
Cancer Sci.
106
559-566
2015
Homo sapiens
25683165
2.3.1.B41
729972
Structure and biochemical functions of SIRT6
J. Biol. Chem.
286
14575-14587
2011
Homo sapiens
21362626
2.3.1.B41
729679
Studying SIRT6 regulation using H3K56 based substrate and small molecules
Eur. J. Pharm. Sci.
63
71-76
2014
Homo sapiens
25004411
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