EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   2.3.1.B41 | 756973 |
Sirt6 suppresses high glucose-induced mitochondrial dysfunction and apoptosis in podocytes through AMPK activation |
Int. J. Biol. Sci. |
15 |
701-713 |
2019 |
Mus musculus C57BL/6 |
30745856 |
| 2.3.1.B41 | 757931 |
SIRT6, a mammalian deacylase with multitasking abilities |
Physiol. Rev. |
100 |
145-169 |
2020 |
Mus musculus |
31437090 |
| 2.3.1.B41 | 757931 |
SIRT6, a mammalian deacylase with multitasking abilities |
Physiol. Rev. |
100 |
145-169 |
2020 |
Homo sapiens |
31437090 |
| 2.3.1.B41 | 757294 |
Sirtuin 6 inhibits myofibroblast differentiation via inactivating transforming growth factor-beta1/Smad2 and nuclear factor-kappaB signaling pathways in human fetal lung fibroblasts |
J. Cell. Biochem. |
120 |
93-104 |
2019 |
Homo sapiens |
30230565 |
| 2.3.1.B41 | 757644 |
Sirtuin6 (SIRT6) promotes the EMT of hepatocellular carcinoma by stimulating autophagic degradation of E-cadherin |
Mol. Cancer Res. |
17 |
2267-2280 |
2019 |
Homo sapiens |
31551254 |
| 2.3.1.B41 | 755787 |
Structural basis of sirtuin 6 activation by synthetic small molecules |
Angew. Chem. Int. Ed. Engl. |
56 |
1007-1011 |
2017 |
Homo sapiens |
27990725 |
| 2.3.1.B41 | 757398 |
Structural basis of sirtuin 6 inhibition by the hydroxamate trichostatin A implications for protein deacylase drug development |
J. Med. Chem. |
61 |
10922-10928 |
2018 |
Homo sapiens |
30395713 |
| 2.3.1.B41 | 757530 |
The deacetylase sirtuin 6 protects against kidney fibrosis by epigenetically blocking beta-catenin targetgene expression |
Kidney Int. |
97 |
106-118 |
2020 |
Homo sapiens |
31787254 |
| 2.3.1.B41 | 758395 |
The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy |
Sci. Rep. |
7 |
11744 |
2017 |
Mus musculus |
28928419 |
| 2.3.1.B41 | 758395 |
The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy |
Sci. Rep. |
7 |
11744 |
2017 |
Homo sapiens |
28928419 |
