4.2.3.B68 | geranylgeranyl diphosphate = spiroalbatene + diphosphate |
cyclization mechanism from GGPP to spiroalbatene involving 1,14-cyclization to cation, followed by a 1,2-hydride migration, another 1,2-hydride shift, and ring closure, followed by a third 1,2-hydride shift and cyclization, yielding a cyclopropane intermediate, and opening of the three-membered ring with concomitant ring closure |
-, 746752 |