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EC Number Reaction Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.52cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine - -
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.52cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine hydrolysis of cyclic di-GMP by a general base-catalyzed mechanism with the assistance of a Mg2+ ion, the essential residue E352 functions as a general base catalyst assisting the deprotonation of Mg2+-coordinated water to generate the nucleophilic hydroxide ion, reaction mechanism, residue positioning, and substrate binding, overview 692857
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