EC Number |
Reaction |
Reference |
---|
3.1.11.1 | Exonucleolytic cleavage in the 3'- to 5'- direction to yield nucleoside 5'-phosphates |
mechanism |
653308 |
3.1.11.1 | Exonucleolytic cleavage in the 3'- to 5'- direction to yield nucleoside 5'-phosphates |
Preference for single-stranded DNA. The E. coli enzyme hydrolyses glucosylated DNA. Formerly EC 3.1.4.25. Similar enzymes: mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases |
- |
3.1.11.1 | Exonucleolytic cleavage in the 3'- to 5'- direction to yield nucleoside 5'-phosphates |
study of interaction between enzyme and mismatch repair proteins MLH1, MLH2 and MLH3. The enzyme binds strongly to MLH1 and forms an immunoprecipitable complex with MLH1/MLH2 in vivo |
652161 |
3.1.11.1 | Exonucleolytic cleavage in the 3'- to 5'- direction to yield nucleoside 5'-phosphates |
the enzyme is involved in mismatch repair and participates directly in somatic hypermutation and class-switch recombination |
666421 |