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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.53synthesis (R)-10-hydroxyoctadecanoic acid, produced by the oleate hydratase is a precursor for gamma-dodecalactone which is an important fragrance and flavour compound 747562
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.53synthesis one of the largest bottlenecks in producing lactones is the hydroxylation of the fatty acids. The exploitation of oleate hydratase to hydrate oleic acid, which can easily be turned into gamma-dodecalactone after beta-elimination, is therefore the perfect solution to produce this valuable compound from cheap renewable materials (e.g. vegetable oil). The specificity and enantioselectivity of the enzyme will provide the correct lactone 747562
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