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3.5.1.B15
diagnostics
the pyrazinamidase activity in pyrazinamide (PZA)-resistant isolates is an important parameter to determine the susceptibility to pyrazinoic acid (PZA) because PZase converts PZA into pyrazinoic acid, which is protonated and becomes active against the mycobacterium. A nonfunctional PZase allows the mycobacterium to survive in the presence of PZA
755800
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