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2.7.1.127
diagnostics
in lung and breast cancer expression of ITPKA is stimulated by gene body methylation, ITPKA gene body methylation occurs early in tumor development. ITPKA enzyme expression may serve as biomarker for early detection of lung cancer
760540
2.7.1.127
medicine
the actin bundling enzyme inositol-trisphosphate 3-kinase A (ITPKA) is a target in tumor therapy, because it is upregulated in tumor but not in corresponding normal cells. Downregulation of ITPKA in lung adenocarcinoma cancers reduced both, tumor growth and metastasis
760540
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