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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.232synthesis production of sakuranetin (7-O-methylnaringenin) and ponciretin (4-O-methylnaringenin) in Escherichia coli by reconstruction of the naringenin biosynthesis pathway. Engineering the shikimic acid pathway, and overexpression of several genes for the biosynthesis of ponciretin and sakuranetin such as tyrosine ammonia lyase, 4-coumaroyl CoA ligase, chalcone synthase, and O-methyltransferase and deletion of isocitrate dehydrogenase finally gives ponciretin and sakuranetin from glucose in Escherichia coli at the concentration of 42.5 mg/l and 40.1 mg/l, respectively 757077
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.232synthesis the recombinant SaOMT is used for 7-O-methylation of naringenin in recombinantly engineered production of 7-O-methyl aromadendrin, which is important in medicinal applications, via sakuranetin from 4-coumaric acid in Escherichia coli, overview -, 718652
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