EC Number |
Application |
Reference |
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1.8.3.3 | analysis |
development of a glutathione micro-enzyme sensor for amperometric detection in vivo, immobilization of enzyme on microelectrode tips |
394887 |
1.8.3.3 | analysis |
development of amperometric glutathione electrodes with immobilized enzyme for detection of H2O2 |
394888 |
1.8.3.3 | analysis |
development of an amperometric biosensor for determination of glutathione, by immobilizing covalently a glutathione oxidase onto the surface of gold coated magnetic nanoparticles modified Pt electrode. The electrode shows maximum response within 4 s, when polarizes at +0.4 V, pH 7.0 and 25°C. There is a linear relationship between electrode response and glutathione concentrations in the range 5.0-4000 microM with a detection limit of 0.1 microM. The biosensor shows 50% loss in its initial activity after its 150 uses over a period 4 months. Glutathione concentration in hemolysated erythrocytes as measured by the present biosensor is 2.8 mM in apparently healthy persons |
725145 |
1.8.3.3 | medicine |
ALT-2074, a catalytic mimic of glutathione oxidase, inhibits human cytochrome P450 3A isoforms in vitro |
711620 |