EC Number   |
Application |
Reference |
|---|
   1.21.99.3 | medicine |
expression and function of the 5-deiodinase and 5-deiodinase isozymes are sensitive to thyroid hormone status, various cytokines and growth factors, severe illness, reactive oxygen species, a variety of hormones and signaling compounds, circadian rythm, and pharmacological agents, and therefore might be useful in sensor function of physiology and pathophysiology |
644806 |
| 1.21.99.3 | medicine |
sonic hedgehog pathway plays a critical role in hair follicle physiology and is constitutively active in basal cell carcinomas, induces D3 in proliferating keratinocytes and in BCCs through Gli2, reversing this T3 deficiency may be a therapeutic approach for BCCs and perhaps other D3-expressing tumors |
689755 |
| 1.21.99.3 | medicine |
sonic hedgehog pathway plays a critical role in hair follicle physiology and is constitutively active in basal cell carcinomas, induces TYPE 3 DEIODINASE in proliferating keratinocytes and in BCCs through Gli2, reversing this T3 deficiency may be a therapeutic approach for BCCs and perhaps other TYPE 3 DEIODINASE-expressing tumors |
689755 |
| 1.21.99.3 | medicine |
type 3 deiodinase activity is robustly induced 1 week after myocardial infarction only in the infarcted myocardium and leads to an acute decrease in serum T4 and T3 after infarction |
686408 |
