EC Number   |
Natural Substrates |
|---|
   5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n |
- |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n |
- |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n |
alternating site ATPase pathway, including a captive head state as an intermediate in the kinesin ATPase cycle |
| 5.6.1.3 | more |
animals survive lowered amounts of KIF3A and KIF3B through heterozygosity. Only in complete absence of KI3A do photoreceptor cells die, and homozygous null mutants of Kif3a are embryonic lethal in mice |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n |
conventional kinesin is required for the microtubule plus-end accumulation of cytoplasmic dynein and dynactin but not for NUDF |
| 5.6.1.3 | more |
during morphogenesis of the Drosophila embryo mitotic spindle, KLP61F's crosslinking and sliding activities can facilitate the gradual accumulation of KLP61F within antiparallel interpolar microtubules at the equator, where the motor can generate force to drive poleward flux and pole-pole separation |
| 5.6.1.3 | more |
during the ATP-waiting state, the mobile tethered head of kinesin1 containing ADP can transiently interact with the microtubule |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n |
Eh Klp5 is a divergent member of the kinesin 5 family that regulates genome content and microtubular assembly |
| 5.6.1.3 | more |
enzyme TbKIN-D associates with cytoskeletal microtubules in vivo, and TbKIN-D interacts with TbKIN-C, a kinetoplastid-specific kinesin |
| 5.6.1.3 | more |
full-length Eg5's motility comprises an unbiased, diffusive mode independent of ATP hydrolysis and a plus end-directed processive mode that requires ATP hydrolysis, Eg5 can switch from diffusive motility to directional motility upon binding to a second microtubule |
