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Results 1 - 6 of 6

EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.8.1.9	(R)-2-chloropropionic acid + H2O	-
3.8.1.9	(R)-2-haloacid + H2O	-
3.8.1.9	DL-2,3-dichloropropionate + H2O	-
3.8.1.9	monobromoacetate + H2O	-
3.8.1.9	monochloroacetate + H2O	-
3.8.1.9	more	the D-2-haloacid dehalogenase of D-specific dehalogenase (DehD) from Rhizobium sp. RC1 catalyses the hydrolytic dehalogenation of D-haloalkanoic acids, inverting the substrate-product configuration and thereby forming the corresponding L-hydroxyalkanoic acids. Molecular docking of substrates into the active site of the DehD mutants R134A and Y135A, which produce altered catalytic functions. The mutants interact strongly with substrates that wild-type DehD does not interact with or degrade. The interaction is particularly enhanced with 3-chloropropionate, in addition to monobromoacetate, monochloroacetate and D,L-2,3-dichloropropionate. The mutants exhibit a strong interaction with 3-chloropropionate at Arg134

Results 1 - 6 of 6

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Release 2023.1 (January 2023)