EC Number |
Natural Substrates |
---|
3.5.1.3 | 2-oxoglutaramate + H2O |
- |
3.5.1.3 | more |
- |
3.5.1.3 | 2-oxoglutaramate + H2O |
alpha-ketoglutaramate |
3.5.1.3 | 2-oxosuccinamate + H2O |
alpha-ketosuccinamate |
3.5.1.3 | more |
conversion of glutamine into alpha-ketoglutarate and ammonia is brought about by two distinct enzymes: glutamine transaminase and omega-amidase |
3.5.1.3 | more |
enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine |
3.5.1.3 | more |
enzyme, in conjunction with glutamine transaminase comprises enzyme system previously designated glutaminase II, involved in metabolism of glutamine |
3.5.1.3 | 2-oxoglutaramate + H2O |
glutamine transaminase and omega-amidase potentially act in tandem to close the methionine salvage cycle in bacteria and plants |
3.5.1.3 | more |
glutamine-transaminase-omega-amidase pathway, metabolic role: utilization of glutamine, formation of ammonia, ammoniagenesis, and utilization of certain alpha-keto acids for synthesis of corresponding amino acids |
3.5.1.3 | more |
high concentrations of omega-amidase in choroid plexus and in the S1-S3 region of nephron suggest that the glutaminase II pathway may generate appreciable ammonia locally in these organs, perhaps in association with transport |