EC Number   |
Natural Substrates |
|---|
   3.4.21.116 | CtpB + H2O |
activation of CtpB |
| 3.4.21.116 | CtpB + H2O |
cleavage is not required to activate CtpB protease activity |
| 3.4.21.116 | more |
critical component of the intercompartmental signal-transduction pathway that activates the sigma factor, sigmaK, in the mother cell of the sporulating cell, possible non-signalling function in germ cell wall biosynthesis and the formation of heat-resistant spores |
| 3.4.21.116 | more |
enzyme is a critical component of the sigmaK regulatory checkpoint during spore formation, PDZ domain can interact with BofC |
| 3.4.21.116 | more |
initiates proteolytic processing of pro-sigmaK to its mature and active form in the opposed mother cell chamber of the developing cell, interacts with BofC |
| 3.4.21.116 | more |
autoproteolytical activation. PDZ domain of enzyme binds to enzyme N-terminus to maintain its zymogen form. Following secretion across a spore membrane, domain binds in trans to the C-terminus of another enzyme molecule thus facilitating first cleavage event of enzyme near the N-terminus which releases the enzyme from the forespore membrane |
| 3.4.21.116 | more |
BofA is unsuitable as a substrate |
| 3.4.21.116 | more |
self cleavage |
| 3.4.21.116 | more |
self cleavage into at least three distinct species of 46, 45, and 44 kDa |
| 3.4.21.116 | pro-sigmaK |
enzyme is essential for intercompartmental signalling in the sigmaK-checkpoint, activates poteolytic processing of pro-sigmaK to its mature and active form sigmaK, function in formation of heat-resistant spores |
