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EC Number	Natural Substrates	Commentary (Nat. Sub.)
2.7.7.102	NTP + 7 dNTP	primases are specialized DNA-dependent RNA polymerases that synthesize a short oligoribonucleotide complementary to single-stranded template DNA. In the context of cellular DNA replication, primases are indispensable since DNA polymerases are not able to start DNA polymerization de novo
2.7.7.102	ssDNA + n dNTP	primases have a fundamental role in DNA replication. They synthesize a primer that is then extended by DNA polymerases

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Release 2023.1 (January 2023)