EC Number |
Natural Substrates |
---|
2.7.1.167 | D-glycero-D-manno-heptose 7-phosphate + ATP |
synthesis of ADP-D-beta-D-heptose in Escherichia coli requires three proteins, GmhA (sedoheptulose 7-phosphate isomerase), HldE (bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase), and GmhB (D,D-heptose 1,7-bisphosphate phosphatase) |
2.7.1.167 | D-glycero-D-manno-heptose 7-phosphate + ATP |
exclusively forming the beta-anomer, namely, D-glycero-beta-D-manno-heptose-1,7-bisphosphate |
2.7.1.167 | D-glycero-D-manno-heptose 7-phosphate + ATP |
- |
2.7.1.167 | more |
involved in the formation of ADP-L-glycero-D-manno-heptose |
2.7.1.167 | more |
rfaE encodes a bifunctional protein. It is proposed that domain I is involved in the synthesis of D-glycero-D-manno-heptose 1-phosphate, whereas domain II catalyzes the ADP transfer to form ADP-D-glycero-D-manno-heptose |