EC Number |
Natural Substrates |
---|
2.4.1.212 | UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan] |
- |
2.4.1.212 | UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] |
- |
2.4.1.212 | UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan] |
- |
2.4.1.212 | UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] |
- |
2.4.1.212 | UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate |
- |
2.4.1.212 | UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate |
addition of monosaccharides to the linear heteropolysaccharide chain |
2.4.1.212 | UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate |
addition of monosaccharides to the reducing end to form a linear heteropolysaccharide chain |
2.4.1.212 | UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate |
biosynthesis of hyaluronan |
2.4.1.212 | more |
enzyme is responsible for hyaluronan biosynthesis, the hyaluronan capsule is an important, but not the only, virulence factor, physiological role of the enzyme |
2.4.1.212 | more |
HA made by the has-1 transduced arterial smooth muscle cells is larger or part of a larger complex that resists proteolytic degradation when compared to the has-3 tansduced ASMCs. There is evidence that the different has enzymes have an inherent ability to regulate hyaluronan size |